Which symptom might indicate that an antidepressant is not working effectively?

The presence of persistent feelings of sadness and hopelessness suggests that the antidepressant may not be having the desired effect. Antidepressants are typically prescribed to alleviate these very symptoms, and their effectiveness is often evaluated based on the improvement in mood and reduction in feelings of sadness or hopelessness. If a patient continues to experience these negative emotions despite being on medication, it can indicate that the treatment is inadequate or that the specific antidepressant chosen is not suitable for the individual's needs. This situation may warrant a reassessment of the treatment plan or consideration of alternative therapies.

In contrast, sudden bursts of energy and happiness might signify a change, potentially indicating a response to the medication, although it can also be a cause for concern in certain cases, such as in bipolar disorder. Increased social interactions and improved concentration at work are generally seen as positive developments that suggest the medication may be working effectively.