Which antidepressant is often prescribed to help with both depression and sleep disturbances?

Trazodone is frequently prescribed to address both depression and sleep disturbances due to its sedative properties. This medication is classified as a serotonin antagonist and reuptake inhibitor (SARI), which allows it to fundamentally impact mood while also promoting sleep.

Its unique mechanism increases serotonin levels, which can help alleviate depressive symptoms, while its sedating effects are beneficial for patients who struggle with insomnia or other sleep-related issues commonly associated with depression. Many patients find that trazodone not only improves their mood but also aids in achieving better sleep quality, making it a dual-purpose treatment option.

Other antidepressants listed, such as sertraline and venlafaxine, primarily focus on mood elevation and do not have the same level of sedative effect as trazodone. Bupropion is known for its stimulating effects, which can sometimes interfere with sleep. Thus, trazodone stands out as the most effective choice for individuals needing assistance with both depression and sleep disturbances.