What should clinicians monitor in patients starting on lithium, which is not a traditional antidepressant, but used in mood stabilization?

Monitoring renal function and thyroid function tests in patients starting on lithium is crucial due to the pharmacokinetic properties of lithium and its potential side effects. Lithium is primarily excreted through the kidneys, making renal function a significant concern, as impaired kidney function can lead to increased lithium levels and a risk of toxicity.

Additionally, lithium can influence thyroid function, often leading to hypothyroidism over time. Therefore, regular monitoring of thyroid hormones is necessary to ensure that any changes are promptly identified and managed. These tests help in ensuring the safety and efficacy of lithium therapy, allowing clinicians to make informed decisions about treatment and adjustments if necessary.

In comparison, while monitoring blood pressure and heart rate, liver function tests, and a complete blood count may be important in other medication contexts, they are not specifically relevant to the unique side effects and concerns associated with lithium treatment.