What are withdrawal symptoms commonly associated with discontinuing SSRIs?

Withdrawal symptoms from selective serotonin reuptake inhibitors (SSRIs) often manifest as flu-like symptoms, insomnia, and irritability. When an SSRI is suddenly discontinued, the brain, which has adapted to the presence of the medication, may react negatively. The abrupt lack of serotonin reuptake inhibition can lead to a variety of physical and emotional symptoms.

Flu-like symptoms may include headache, fatigue, muscle aches, and nausea, which resemble a viral illness but are actually a result of changes in neurotransmitter levels. Insomnia arises from the disruption of the normal sleep-wake cycle that SSRIs help regulate, leading to difficulty falling or staying asleep. Irritability is a common emotional response due to the sudden change in serotonin levels, which can affect mood stability and lead to increased anxiety.

While visual hallucinations and severe depression are not typical withdrawal symptoms associated with SSRIs, cognitive decline can occur as a separate issue but is not specifically linked to the withdrawal process itself. Understanding these withdrawal symptoms is crucial for managing discontinuation properly and ensuring a smoother transition off these medications.