Selective serotonin reuptake inhibitors are primarily prescribed for which of the following?

Selective serotonin reuptake inhibitors (SSRIs) are primarily prescribed for depression because they function by increasing the levels of serotonin in the brain, a neurotransmitter that plays a crucial role in regulating mood. The mechanism of action involves inhibiting the reuptake of serotonin into the presynaptic cell, thereby making more serotonin available in the synaptic cleft for receptor binding. This enhancement of serotonergic neurotransmission is particularly effective in alleviating the symptoms of depression.

While SSRIs are also used for other conditions, such as anxiety disorders, obsessive-compulsive disorder, and sometimes even attention deficit hyperactivity disorder, their primary indication remains major depressive disorder. The extensive research and clinical practice surrounding SSRIs have solidified their position as first-line treatment options for depression, leading to their widespread use in clinical settings for this specific purpose.